Interleukin 17a antibody

Catalog No. ABIN6964029

The Rat Monoclonal anti-Interleukin 17a antibody has been validated for Neut. It is suitable to detect Interleukin 17a in samples from Mouse. There are 3+ publications available.

Quick Overview for Interleukin 17a antibody (ABIN6964029)

Target: Interleukin 17a (IL17A) (Interleukin 17A (IL17A))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This Interleukin 17a antibody is un-conjugated

Application: Neutralization (Neut)

Clone: TC11-18H10

Product Details anti-Interleukin 17a Antibody

Specificity: Native and recombinant mouse IL-17A.

Purification: Purified from in vitro cultures by protein G affinity chromatography.

Immunogen: Recombinant mouse IL-17

Isotype: IgG1

Application Details

Application Notes: Neutralization of mouse IL-17A bioactivity. It is recommended to establish the optimal antibody concentration for the assay system used.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: supplied at 0.5 mg/mL in PBS free of preservatives

Preservative: Without preservative

Storage: 4 °C,-20 °C

Storage Comment: Store product at 4-8°C or frozen at -20°C or below. Avoid repeated freezing/ thawing.

Expiry Date: 18 months

References for anti-Interleukin 17a antibody (ABIN6964029)

He, Li, Yusuf, Elmets, Li, Mountz, Xu: "IL-17 promotes tumor development through the induction of tumor promoting microenvironments at tumor sites and myeloid-derived suppressor cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 184, Issue 5, pp. 2281-8, (2010) (PubMed).

Mangalam, Luckey, Basal, Jackson, Smart, Rodriguez, David: "HLA-DQ8 (DQB1*0302)-restricted Th17 cells exacerbate experimental autoimmune encephalomyelitis in HLA-DR3-transgenic mice." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 182, Issue 8, pp. 5131-9, (2009) (PubMed).

Yen, Cheung, Scheerens, Poulet, McClanahan, McKenzie, Kleinschek, Owyang, Mattson, Blumenschein, Murphy, Sathe, Cua, Kastelein, Rennick: "IL-23 is essential for T cell-mediated colitis and promotes inflammation via IL-17 and IL-6." in: The Journal of clinical investigation, Vol. 116, Issue 5, pp. 1310-6, (2006) (PubMed).

Target Details for Interleukin 17a

Target: Interleukin 17a (IL17A) (Interleukin 17A (IL17A))

Alternative Name: IL17A

Gene ID: 16171