CHAF1B antibody
Quick Overview for CHAF1B antibody (ABIN6971490)
Target
See all CHAF1B AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Characteristics
- CAF-1 p60 (Chromatin assembly factor-1 p60 subunit, CAF1B, CHAF1B) is a subunit of the CAF-1 complex that is required for the assembly of nucleosomes onto newly replicated DNA. Specifically, CAF-1 assists in the loading of the H3-H4 tetramer and may be involved in DNA damage repair. CAF-1 p60 is a WD-repeat containing protein related to HIRA. CAF-1 p60 antibody (mAb) (Clone 24) was raised in a Mouse host. It has been validated for use in Immunocytochemistry, Immunofluorescence, Immunoprecipitation and Western blot, it has been shown to react with Human and Mouse samples.
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Purification
- Protein G Chromatography
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Immunogen
- The CAF-1 p60 antobody was raised against full-length CAF-1 purified from human 293 cells.
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Isotype
- IgG1
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Buffer
- Purified IgG in 70 mM Tris ( pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30 % glycerol and 0.035 % sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
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- CHAF1B (Chromatin Assembly Factor 1, Subunit B (p60) (CHAF1B))
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Alternative Name
- CAF-1 p60
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Molecular Weight
- 60 kDa
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NCBI Accession
- NP_005432
Target
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