CENPB antibody (C-Term)

Catalog No. ABIN6971523

Product Details anti-CENPB Antibody

Target: CENPB (Centromere Protein B (CENPB))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CENPB antibody is un-conjugated

Application: Immunofluorescence (IF), Immunocytochemistry (ICC)

Characteristics: CENP-B (Centromere protein B) is a protein associated with centromeric DNA and crucial to the formation of the special chromatin structure on the a-satellite DNA repeats of the human centromere. CENP-B specifically binds a 17 bp sequence which may function as a cis-element for centromere-specific nucleosome assembly. CENP-B plays a role in the organization of centromere satellite DNA into a higher order structure, directing centromere formation and kinetochore assembly in mammalian chromosomes. CENP-B antibody (pAb) was raised in a Rabbit host. It has been validated for use in Immunocytochemistry and Immunofluorescence, it has been shown to react with Human samples.

Purification: Protein A Chromatography

Immunogen: This CENP-B antibody was raised against a recombinant protein corresponding to the C-terminal region of human CENP-B.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: Purified rabbit IgG in PBS with 30 % glycerol and 0.035 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Target Details for CENPB

Target: CENPB (Centromere Protein B (CENPB))

Alternative Name: CENP-B (CENPB Products)

Molecular Weight: 67 kDa

NCBI Accession: NP_001801