CXXC4 antibody (N-Term)

Catalog No. ABIN6971565

The Rabbit Polyclonal anti-CXXC4 antibody has been validated for WB. It is suitable to detect CXXC4 in samples from Human and Mouse.

Quick Overview for CXXC4 antibody (N-Term) (ABIN6971565)

Target: CXXC4 (CXXC Finger Protein 4 (CXXC4))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CXXC4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CXXC4 Antibody

Binding Specificity: N-Term

Characteristics: Cxxc4 (CXXC Finger Protein 4) acts as a negative regulator of the Wnt signaling pathway via its interaction with DVL1 and has been implicated in malignant renal cell carcinoma and colonic villous adenoma. Recently, Cxxc4 has been shown to be involved in the regulation of DNA demethylation. It binds to unmethylated CpGs in DNA and is involved in TET2 downregulation. Cxxc4 antibody (pAb) was raised in a Rabbit host. It has been validated for use in Western blot, it has been shown to react with Human and Mouse samples.

Purification: Affinity Purified

Immunogen: This antibody was raised against a peptide within the N-terminal region of mouse Cxxc4.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Target Details for CXXC4

Target: CXXC4 (CXXC Finger Protein 4 (CXXC4))

Alternative Name: Cxxc4

Molecular Weight: 42 kDa

NCBI Accession: NP_001004367