GLI1 antibody (C-Term)

Catalog No. ABIN6971684

This Rabbit Polyclonal antibody specifically detects GLI1 in WB. It exhibits reactivity toward Human.

Quick Overview for GLI1 antibody (C-Term) (ABIN6971684)

Target: GLI1 (Zinc Finger Protein GLI1 (GLI1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GLI1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GLI1 Antibody

Binding Specificity: C-Term

Characteristics: GLI1 (Glioma-associated oncogene 1) is a zinc finger transcription factor and oncogene. GLI1 is part of the hedgehog signaling pathway, but is also activated in response to TGF-b signaling as well. GLI1 activates transcription of a number of genes that promote cell cycle progression. GLI1 is overexpressed as a result of constitutive activation of hedgehog signaling, which plays a role in the initiation of cancer. GLI1 also promotes self-renewal of neural stem cells. GLI1 antibody (pAb) was raised in a Rabbit host. It has been validated for use in Western blot, it has been shown to react with Human samples.

Purification: Affinity Purified

Immunogen: This GLI1 antibody was raised against a peptide within the C-terminal region of human GLI1.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Target Details for GLI1

Target: GLI1 (Zinc Finger Protein GLI1 (GLI1))

Alternative Name: GLI1

Molecular Weight: 120 kDa

NCBI Accession: NP_005260

Pathways: Hedgehog Signaling, Dopaminergic Neurogenesis