MYCN antibody (C-Term)

Catalog No. ABIN6972393

The Rabbit Polyclonal anti-MYCN antibody has been validated for WB and ChIP-seq. It is suitable to detect MYCN in samples from Human.

Quick Overview for MYCN antibody (C-Term) (ABIN6972393)

Target: MYCN (N-Myc Proto-Oncogene Protein (MYCN))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MYCN antibody is un-conjugated

Application: Western Blotting (WB), ChIP DNA-Sequencing (ChIP-seq)

Product Details anti-MYCN Antibody

Binding Specificity: C-Term

Characteristics: N-Myc (MYCN) is a member of the Myc family of proto-oncogenes. Myc family members play crucial roles in regulating cell proliferation, size and differentiation. N-Myc is required for proper development of the nervous system. Myc family proteins can induce malignant transformation inappropriately modulating gene transcription, leading to unchecked cell proliferation. Misexpression of N-Myc is often associated with pediatric neural cancers such as neuroblastoma, medulloblastoma and retinoblastoma. N-Myc antibody (pAb) was raised in a Rabbit host. It has been validated for use in ChIP-Seq and Western blot, it has been shown to react with Human samples.

Purification: Affinity Purified

Immunogen: This N-Myc antibody was raised against a peptide derived from the C-terminal region of human N-Myc.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: Purified IgG in 70 mM Tris ( pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30 % glycerol and 0.035 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Target Details for MYCN

Target: MYCN (N-Myc Proto-Oncogene Protein (MYCN))

Alternative Name: N-Myc

Molecular Weight: 60 kDa

NCBI Accession: NP_005369