NRF1 antibody (C-Term)
Quick Overview for NRF1 antibody (C-Term) (ABIN6972449)
Target
See all NRF1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- C-Term
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Characteristics
- NRF1 (Nuclear Respiratory Factor 1) is a transcription factor that activates the expression of the EIF2S1 (EIF2-alpha) gene. Links the transcriptional modulation of key metabolic genes to cellular growth and development. Implicated in the control of nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication. NRF1 antibody (pAb) was raised in a Rabbit host. It has been validated for use in Western blot, it has been shown to react with Human and Mouse samples.
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Purification
- Affinity Purified
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Immunogen
- This antibody was raised against a peptide within the C-terminal region of human NRF1.
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Isotype
- IgG
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Buffer
- Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
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- NRF1 (Nuclear Respiratory Factor 1 (NRF1))
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Alternative Name
- NRF1
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Molecular Weight
- 68 kDa
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NCBI Accession
- NP_001280092
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Pathways
- Regulation of Lipid Metabolism by PPARalpha
Target
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