Parvin alpha antibody (pSer8) (AbBy Fluor® 350)

Catalog No. ABIN6976868

The Rabbit Polyclonal anti-Parvin alpha antibody has been validated for WB, IF (cc) and IF (p). It is suitable to detect Parvin alpha in samples from Mouse.

Quick Overview for Parvin alpha antibody (pSer8) (AbBy Fluor® 350) (ABIN6976868)

Target: Parvin alpha (PARVA) (Parvin, alpha (PARVA))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Parvin alpha antibody is conjugated to AbBy Fluor® 350

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-Parvin alpha Antibody (AbBy Fluor® 350)

Binding Specificity: pSer8

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Cow,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthesised phosphopeptide derived from human Parvin alpha around the phosphorylation site of Ser8

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for Parvin alpha

Target: Parvin alpha (PARVA) (Parvin, alpha (PARVA))

Alternative Name: Parvin alpha

Background:

Synonyms: Parvin alpha (phospho S8), p-Parvin alpha (phospho S8), Actopaxin, Alpha parvin, Alpha-parvin, Calponin like integrin linked kinase binding protein, Calponin-like integrin-linked kinase-binding protein, CH ILKBP, CH-ILKBP, FLJ10793, FLJ12254, Matrix remodelling associated 2, Matrix remodelling associated protein 2, Matrix-remodeling-associated protein 2, MXRA 2, MXRA2, PARV A, PARVA, PARVA_HUMAN.

Background: This gene encodes a member of the parvin family of actin-binding proteins. Parvins are associated with focal contacts and contain calponin homology domains that bind to actin filaments. The encoded protein is part of the integrin-linked kinase signaling complex and plays a role in cell adhesion, motility and survival. [provided by RefSeq, Dec 2010]

Gene ID: 55742

UniProt: Q9NVD7

Pathways: Smooth Muscle Cell Migration