PLEKHA1 antibody (AA 111-210) (AbBy Fluor® 488)

Catalog No. ABIN6977331

The AbBy Fluor® 488-conjugated Rabbit Polyclonal anti-PLEKHA1 antibody (ABIN6977331) specifically detects PLEKHA1 in WB, IF (cc) and IF (p). The antibody is reactive with Mouse samples.

Quick Overview for PLEKHA1 antibody (AA 111-210) (AbBy Fluor® 488) (ABIN6977331)

Target: PLEKHA1 (Pleckstrin Homology Domain Containing, Family A (phosphoinositide Binding Specific) Member 1 (PLEKHA1))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PLEKHA1 antibody is conjugated to AbBy Fluor® 488

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-PLEKHA1 Antibody (AbBy Fluor® 488)

Binding Specificity: AA 111-210

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Cow,Sheep,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PLEKHA1

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for PLEKHA1

Target: PLEKHA1 (Pleckstrin Homology Domain Containing, Family A (phosphoinositide Binding Specific) Member 1 (PLEKHA1))

Alternative Name: PLEKHA1

Background:

Synonyms: OTTHUMP00000020651, PH domain containing family A member 1, PH domain-containing family A member 1, PKHA1_HUMAN, Pleckstrin homology domain containing family A member 1, Pleckstrin homology domain containing, family A (phosphoinositide binding specific) member, Pleckstrin homology domain-containing family A member 1, PLEKHA1, Tandem PH domain containing protein 1, Tandem PH domain-containing protein 1, TAPP 1, TAPP-1, TAPP1.

Background: This gene encodes a pleckstrin homology domain-containing adapter protein. The encoded protein is localized to the plasma membrane where it specifically binds phosphatidylinositol 3,4-bisphosphate. This protein may be involved in the formation of signaling complexes in the plasma membrane. Polymorphisms in this gene are associated with age-related macular degeneration. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 5.[provided by RefSeq, Sep 2010]

Gene ID: 59338

UniProt: Q9HB21

Pathways: Platelet-derived growth Factor Receptor Signaling