PSMC3 antibody (AA 212-220) (AbBy Fluor® 555)

Catalog No. ABIN6978546

The AbBy Fluor® 555-conjugated Rabbit Polyclonal anti-PSMC3 antibody (ABIN6978546) specifically detects PSMC3 in WB, IF (cc) and IF (p). The antibody is reactive with Human, Mouse and Xenopus laevis samples.

Quick Overview for PSMC3 antibody (AA 212-220) (AbBy Fluor® 555) (ABIN6978546)

Target: PSMC3 (Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 3 (PSMC3))

Reactivity: Human, Mouse, Xenopus laevis

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PSMC3 antibody is conjugated to AbBy Fluor® 555

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-PSMC3 Antibody (AbBy Fluor® 555)

Binding Specificity: AA 212-220

Cross-Reactivity: Human, Mouse, Xenopus laevis

Predicted Reactivity: Dog,Cow,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PSMC3

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for PSMC3

Target: PSMC3 (Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 3 (PSMC3))

Alternative Name: PSMC3

Background:

Synonyms: 26S protease regulatory subunit 6A, 26S proteasome AAA-ATPase subunit RPT5, Human immunodeficiency virus tat transactivator binding protein 1, MGC8487, Proteasome (prosome macropain) 26S subunit ATPase 3, Proteasome 26S ATPase subunit 3, Proteasome 26S subunit ATPase 3, Proteasome subunit P50, PRS6A_HUMAN, PSMC 3, PSMC3, Tat binding protein 1, TAT-binding protein 1, TBP-1, TBP1.

Background: The 26S protease is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex (By similarity). In case of HIV-1 infection, suppresses Tat-mediated transactivation.

Gene ID: 5702

UniProt: P17980

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway