Pleiotrophin antibody (AbBy Fluor® 555)

Catalog No. ABIN6978760

This Rabbit Polyclonal antibody specifically detects Pleiotrophin in IF (cc) and IF (p). It exhibits reactivity toward Human.

Quick Overview for Pleiotrophin antibody (AbBy Fluor® 555) (ABIN6978760)

Target: Pleiotrophin (PTN)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Pleiotrophin antibody is conjugated to AbBy Fluor® 555

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-Pleiotrophin Antibody (AbBy Fluor® 555)

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PTN

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for Pleiotrophin

Target: Pleiotrophin (PTN)

Alternative Name: PTN

Background:

Synonyms: pleiotrophin, HARP, HBBM, HBGAM, HBGF8, HBNF, HBNF1, Heparin Binding Growth Factor 8, Heparin binding neurite outgrowth promoting factor 1, heparin-binding growth associated molecule, NEGF1, Neurite Growth Promoting Factor 1, OSF-1, osteoblast-specific factor, PTN, PTN_HUMAN.

Background: Secreted growth factor that induces neurite outgrowth and which is mitogenic for fibroblasts, epithelial, and endothelial cells. Binds anaplastic lymphoma kinase (ALK) which induces MAPK pathway activation, an important step in the anti-apoptotic signaling of PTN and regulation of cell proliferation.

Gene ID: 5764

UniProt: P21246

Pathways: RTK Signaling