PD-L1 antibody (AA 61-160) (AbBy Fluor® 555)

Catalog No. ABIN6978862

This Rabbit Polyclonal antibody specifically detects PD-L1 in WB and FACS. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for PD-L1 antibody (AA 61-160) (AbBy Fluor® 555) (ABIN6978862)

Target: PD-L1 (CD274 (PD-L1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PD-L1 antibody is conjugated to AbBy Fluor® 555

Application: Western Blotting (WB), Flow Cytometry (FACS)

Product Details anti-PD-L1 Antibody (AbBy Fluor® 555)

Binding Specificity: AA 61-160

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Cow,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CD274

Isotype: IgG

Application Details

Application Notes: FCM 1:20-100

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for PD-L1

Target: PD-L1 (CD274 (PD-L1))

Alternative Name: CD274

Background:

Synonyms: B7-H1, PD-L1, CD274, Programmed cell death 1 ligand 1, Programmed death ligand 1, PD-L1, PDCD1 ligand 1, B7 homolog 1, B7-H1, Programmed death ligand 1, PD1L1_HUMAN.

Background: Programmed cell death 1 ligand 1(Programmed death ligand 1, PD-L1, PDCD1 ligand 1, B7 homolog 1, B7-H1, CD274) involved in the costimulatory signal, essential for T lymphocyte proliferation and production of IL10 and IFNG, in an IL2-dependent and a PDCD1-independent manner. Interaction with PDCD1 inhibit T-cell proliferation and cytokine production.

Gene ID: 8324

Pathways: Cancer Immune Checkpoints