Parvin alpha antibody (pSer8) (AbBy Fluor® 647)

Catalog No. ABIN6980244

This anti-Parvin alpha antibody is a Rabbit Polyclonal antibody detecting Parvin alpha in WB, IF (cc) and IF (p). Suitable for Mouse.

Quick Overview for Parvin alpha antibody (pSer8) (AbBy Fluor® 647) (ABIN6980244)

Target: Parvin alpha (PARVA) (Parvin, alpha (PARVA))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Parvin alpha antibody is conjugated to AbBy Fluor® 647

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-Parvin alpha Antibody (AbBy Fluor® 647)

Binding Specificity: pSer8

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Cow,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthesised phosphopeptide derived from human Parvin alpha around the phosphorylation site of Ser8

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for Parvin alpha

Target: Parvin alpha (PARVA) (Parvin, alpha (PARVA))

Alternative Name: Parvin alpha

Background:

Synonyms: Parvin alpha (phospho S8), p-Parvin alpha (phospho S8), Actopaxin, Alpha parvin, Alpha-parvin, Calponin like integrin linked kinase binding protein, Calponin-like integrin-linked kinase-binding protein, CH ILKBP, CH-ILKBP, FLJ10793, FLJ12254, Matrix remodelling associated 2, Matrix remodelling associated protein 2, Matrix-remodeling-associated protein 2, MXRA 2, MXRA2, PARV A, PARVA, PARVA_HUMAN.

Background: This gene encodes a member of the parvin family of actin-binding proteins. Parvins are associated with focal contacts and contain calponin homology domains that bind to actin filaments. The encoded protein is part of the integrin-linked kinase signaling complex and plays a role in cell adhesion, motility and survival. [provided by RefSeq, Dec 2010]

Gene ID: 55742

UniProt: Q9NVD7

Pathways: Smooth Muscle Cell Migration