PD-L1 antibody (AA 31-130) (AbBy Fluor® 647)

Catalog No. ABIN6980420

The Rabbit Polyclonal anti-PD-L1 antibody has been validated for WB, IF (cc) and IF (p). It is suitable to detect PD-L1 in samples from Mouse.

Quick Overview for PD-L1 antibody (AA 31-130) (AbBy Fluor® 647) (ABIN6980420)

Target: PD-L1 (CD274 (PD-L1))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PD-L1 antibody is conjugated to AbBy Fluor® 647

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-PD-L1 Antibody (AbBy Fluor® 647)

Binding Specificity: AA 31-130

Cross-Reactivity: Mouse

Predicted Reactivity: Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from mouse PD-L1

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for PD-L1

Target: PD-L1 (CD274 (PD-L1))

Alternative Name: PD-L1

Background:

Synonyms: CD274, B7 H, B7 H1, B7 homolog 1, B7-H1, B7H, B7H1, CD 274, CD274 antigen, CD274 Molecule, MGC142294, MGC142296, OTTHUMP00000021029, PD L1, PD1L1_HUMAN, PD1L1_Mouse, PDCD1 ligand 1, PDCD1L1, PDCD1LG1, PDL 1, PDL1, Programmed cell death 1 ligand 1, Programmed death ligand 1, RGD1566211.

Background: Involved in the costimulatory signal, essential for T-cell proliferation and production of IL10 and IFNG, in an IL2-dependent and a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation and cytokine production.

Gene ID: 29126

UniProt: Q9EP73

Pathways: Cancer Immune Checkpoints