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SMAD2 antibody (pSer250) (AbBy Fluor® 647)

SMAD2 Reactivity: Human, Mouse WB, FACS Host: Rabbit Polyclonal AbBy Fluor® 647
Catalog No. ABIN6980535
  • Target See all SMAD2 Antibodies
    SMAD2 (SMAD, Mothers Against DPP Homolog 2 (SMAD2))
    Binding Specificity
    • 51
    • 44
    • 29
    • 26
    • 24
    • 22
    • 9
    • 9
    • 8
    • 7
    • 6
    • 6
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer250
    Reactivity
    • 249
    • 159
    • 127
    • 13
    • 10
    • 10
    • 9
    • 8
    • 8
    • 7
    • 7
    • 6
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 247
    • 13
    • 1
    Rabbit
    Clonality
    • 224
    • 37
    Polyclonal
    Conjugate
    • 122
    • 17
    • 12
    • 10
    • 7
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 3
    This SMAD2 antibody is conjugated to AbBy Fluor® 647
    Application
    • 204
    • 98
    • 63
    • 54
    • 53
    • 44
    • 41
    • 40
    • 17
    • 15
    • 12
    • 11
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS)
    Cross-Reactivity
    Human, Mouse
    Predicted Reactivity
    Rat,Dog,Cow,Pig
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthesised phosphopeptide derived from human Smad2 around the phosphorylation site of Ser250
    Isotype
    IgG
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  • Application Notes
    FCM 1:20-100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    SMAD2 (SMAD, Mothers Against DPP Homolog 2 (SMAD2))
    Alternative Name
    Smad2 (SMAD2 Products)
    Background

    Synonyms: Smad2 (phospho S250), p-Smad2 (phospho S250), hMAD 2, hMAD 3, hSMAD2, hSMAD3, Mad related protein 2, MADH2, MADH3, MADR2, Mothers against DPP homolog 2, Mothers against DPP homolog 3, Sma and Mad related protein 2, SMA and MAD related protein 3, SMAD 2, SMAD 3, SMAD family member 2, SMAD family member 3.

    Background: Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD2/SMAD4 complex, activates transcription. May act as a tumor suppressor in colorectal carcinoma.

    Gene ID
    4087
    UniProt
    Q15796
    Pathways
    Cell Division Cycle, Hormone Transport, Chromatin Binding, Protein targeting to Nucleus
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