UMPS antibody (AA 351-450) (AbBy Fluor® 647)
Quick Overview for UMPS antibody (AA 351-450) (AbBy Fluor® 647) (ABIN6980539)
Target
See all UMPS AntibodiesReactivity
Host
Clonality
Conjugate
Application
-
-
Binding Specificity
- AA 351-450
-
Cross-Reactivity
- Cynomolgus, Human, Rhesus Monkey
-
Predicted Reactivity
- Mouse,Rat,Dog,Cow,Sheep,Horse,Rabbit
-
Purification
- Purified by Protein A.
-
Immunogen
- KLH conjugated synthetic peptide derived from human UMPS
-
Isotype
- IgG
-
-
-
-
Application Notes
-
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 1 μg/μL
-
Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
-
Preservative
- ProClin
-
Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
-
Storage
- -20 °C
-
Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
-
Expiry Date
- 12 months
-
-
- UMPS (Uridine Monophosphate Synthetase (UMPS))
-
Alternative Name
- UMPS
-
Background
-
Synonyms: Uridine 5'-monophosphate synthase, UMPS, UMP synthase, Orotate phosphoribosyltransferase, OPRT, OPRTase, ODC, OMPdecase, OK/SW-cl.21
Background: This gene encodes a uridine 5'-monophosphate synthase. The encoded protein is a bifunctional enzyme that catalyzes the final two steps of the de novo pyrimidine biosynthetic pathway. The first reaction is carried out by the N-terminal enzyme orotate phosphoribosyltransferase which converts orotic acid to orotidine-5'-monophosphate. The terminal reaction is carried out by the C-terminal enzyme OMP decarboxylase which converts orotidine-5'-monophosphate to uridine monophosphate. Defects in this gene are the cause of hereditary orotic aciduria. Alternate splicing results in multiple transcript variants.
-
Gene ID
- 7372
-
UniProt
- P11172
-
Pathways
- Ribonucleoside Biosynthetic Process
Target
-