Ataxin 3 antibody (AA 51-150) (Biotin)

Catalog No. ABIN6982636

This Rabbit Polyclonal antibody specifically detects Ataxin 3 in WB, ELISA, IHC (p) and IHC (fro). It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for Ataxin 3 antibody (AA 51-150) (Biotin) (ABIN6982636)

Target: Ataxin 3 (ATXN3)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Ataxin 3 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-Ataxin 3 Antibody (Biotin)

Binding Specificity: AA 51-150

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Dog,Cow,Sheep,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Ataxin 3

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for Ataxin 3

Target: Ataxin 3 (ATXN3)

Alternative Name: Ataxin 3

Background:

Synonyms: AT3, Ataxin 3, Ataxin-3, ATX3, ATX3_HUMAN, ATXN3, EC 3.4.22., JOS, Josephin, Machado Joseph disease (spinocerebellar ataxia 3, olivopontocerebellar ataxia 3, autosomal dominant, ataxin 3), Machado Joseph disease, Machado Joseph disease protein 1, Machado-Joseph disease protein 1, Machado-Joseph disease protein 1 homolog, MJD, MJD gene, MJD1, Olivopontocerebellar ataxia 3, OTTHUMP00000221583, OTTHUMP00000221585, OTTHUMP00000221586, OTTHUMP00000221587, OTTHUMP00000231995, OTTHUMP00000231997, Rsca3, SCA3, SCA3 gene, Spinocerebellar ataxia type 3 protein.

Background: Interacts with key regulators (CBP, p300 and PCAF) of transcription and represses transcription. Acts as a histone-binding protein that regulates transcription. Acts as a deubiquitinating enzyme.

Gene ID: 4287

UniProt: P54252