RSPO1 antibody (AA 31-130) (Biotin)

Catalog No. ABIN6982799

The Rabbit Polyclonal anti-RSPO1 antibody has been validated for IHC (p). It is suitable to detect RSPO1 in samples from Human, Rat, Mouse, Cow, Dog, Horse, Pig and Rabbit.

Quick Overview for RSPO1 antibody (AA 31-130) (Biotin) (ABIN6982799)

Target: RSPO1 (R-Spondin 1 (RSPO1))

Reactivity: Human, Rat, Mouse, Cow, Dog, Horse, Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RSPO1 antibody is conjugated to Biotin

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-RSPO1 Antibody (Biotin)

Binding Specificity: AA 31-130

Cross-Reactivity: Cow, Dog, Horse, Human, Mouse, Pig, Rabbit, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human RSPO1

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for RSPO1

Target: RSPO1 (R-Spondin 1 (RSPO1))

Alternative Name: RSPO1

Background:

Synonyms: CRISTIN3, FLJ40906, hRspo1, R spondin homolog (Xenopus laevis), R spondin homolog, R spondin1, R-spondin-1, Roof plate specific spondin, Roof plate-specific spondin-1, RP11-566C13.1, RSPO, Rspo1, RSPO1_HUMAN.

Background: RSPO1 is a member of the R-spondin family and encodes a secreted activator protein with two cystein-rich, furin-like domains and one thrombospondin type 1 domain. In mice, the protein induces the rapid onset of crypt cell proliferation and increases intestinal epithelial healing, providing a protective effect against chemotherapy-induced adverse effects.

Gene ID: 284654

UniProt: Q2MKA7