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PD-L1 antibody (AA 31-130) (Biotin)

This Rabbit Polyclonal antibody specifically detects PD-L1 in WB, ELISA, IHC (p) and IHC (fro). It exhibits reactivity toward Mouse.
Catalog No. ABIN6982837

Quick Overview for PD-L1 antibody (AA 31-130) (Biotin) (ABIN6982837)

Target

See all PD-L1 Antibodies
PD-L1 (CD274 (PD-L1))

Reactivity

  • 274
  • 141
  • 72
  • 6
  • 6
  • 5
  • 5
  • 1
  • 1
Mouse

Host

  • 154
  • 144
  • 20
  • 5
  • 4
  • 4
  • 2
  • 1
Rabbit

Clonality

  • 204
  • 121
  • 7
Polyclonal

Conjugate

  • 158
  • 25
  • 14
  • 12
  • 9
  • 6
  • 6
  • 6
  • 6
  • 6
  • 6
  • 6
  • 5
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
This PD-L1 antibody is conjugated to Biotin

Application

  • 193
  • 146
  • 95
  • 73
  • 45
  • 45
  • 44
  • 40
  • 28
  • 14
  • 11
  • 9
  • 7
  • 7
  • 5
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • Binding Specificity

    • 72
    • 29
    • 16
    • 14
    • 14
    • 11
    • 11
    • 10
    • 7
    • 7
    • 7
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 31-130

    Cross-Reactivity

    Mouse

    Predicted Reactivity

    Rat

    Purification

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from mouse PD-L1

    Isotype

    IgG
  • Application Notes

    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    Preservative

    ProClin

    Precaution of Use

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Storage

    -20 °C

    Storage Comment

    Store at -20°C for 12 months.

    Expiry Date

    12 months
  • Target

    PD-L1 (CD274 (PD-L1))

    Alternative Name

    PD-L1

    Background

    Synonyms: CD274, B7 H, B7 H1, B7 homolog 1, B7-H1, B7H, B7H1, CD 274, CD274 antigen, CD274 Molecule, MGC142294, MGC142296, OTTHUMP00000021029, PD L1, PD1L1_HUMAN, PD1L1_Mouse, PDCD1 ligand 1, PDCD1L1, PDCD1LG1, PDL 1, PDL1, Programmed cell death 1 ligand 1, Programmed death ligand 1, RGD1566211.

    Background: Involved in the costimulatory signal, essential for T-cell proliferation and production of IL10 and IFNG, in an IL2-dependent and a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation and cytokine production.

    Gene ID

    29126

    UniProt

    Q9EP73

    Pathways

    Cancer Immune Checkpoints
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