NKIRAS1 antibody (AA 131-192) (Biotin)

Catalog No. ABIN6982889

The Rabbit Polyclonal anti-NKIRAS1 antibody has been validated for WB, ELISA, IHC (p) and IHC (fro). It is suitable to detect NKIRAS1 in samples from Mouse and Rat.

Quick Overview for NKIRAS1 antibody (AA 131-192) (Biotin) (ABIN6982889)

Target: NKIRAS1 (NFKB Inhibitor Interacting Ras-Like 1 (NKIRAS1))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NKIRAS1 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-NKIRAS1 Antibody (Biotin)

Binding Specificity: AA 131-192

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Human,Dog,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human NKIRAS1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for NKIRAS1

Target: NKIRAS1 (NFKB Inhibitor Interacting Ras-Like 1 (NKIRAS1))

Alternative Name: NKIRAS1

Background:

Synonyms: 2400004O09Rik, I kappa B interacting Ras like protein 1, I-kappa-B-interacting Ras-like protein 1, Kappa B Ras 1, Kappa B Ras protein 1, Kappa B-Ras protein 1, KappaB Ras1, KappaB-Ras1, KBRAS 1, KBRAS1, KBRS1_HUMAN, NF kappa B inhibitor interacting Ras like protein 1, NF-kappa-B inhibitor-interacting Ras-like protein 1, NFKB inhibitor interacting Ras like 1, NFKB inhibitor interacting Ras like protein 1, NKIRAS 1, nkiras1.

Background: Atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation. May act by blocking phosphorylation of NFKBIB and mediating cytoplasmic retention of p65/RELA NF-kappa-B subunit. It is unclear whether it acts as a GTPase. Both GTP- and GDP-bound forms block phosphorylation of NFKBIB.

Gene ID: 28512

UniProt: Q9NYS0