CCL2 antibody (AA 51-148) (Cy3)

Catalog No. ABIN6983923

This Rabbit Polyclonal antibody specifically detects CCL2 in IF (p) and IF (cc). It exhibits reactivity toward Rat.

Quick Overview for CCL2 antibody (AA 51-148) (Cy3) (ABIN6983923)

Target: CCL2 (Chemokine (C-C Motif) Ligand 2 (CCL2))

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCL2 antibody is conjugated to Cy3

Application: Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Product Details anti-CCL2 Antibody (Cy3)

Binding Specificity: AA 51-148

Cross-Reactivity: Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from rat MCP1

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for CCL2

Target: CCL2 (Chemokine (C-C Motif) Ligand 2 (CCL2))

Alternative Name: MCP1

Background:

Synonyms: C-C motif chemokine 2, CCL 2, CCL2, CCL2_HUMAN, Chemokine (C C motif) ligand 2, Chemokine C C motif ligand 2, Chemokine CC Motif Ligand 2, GDCF 2, GDCF 2 HC11, GDCF-2, GDCF2, HC11, HSMCR30, HSMCR30, JE, MCAF, MCP 1, MCP-1, MCP1, MGC9434, Monocyte chemoattractant protein 1, Monocyte chemotactic and activating factor, Monocyte chemotactic protein 1, Monocyte secretory protein JE, SCYA2, Small inducible cytokine A2 (monocyte chemotactic protein 1, homologous to mouse Sig je), Small inducible cytokine A2, Small inducible cytokine subfamily A (Cys Cys), member 2, Small inducible cytokine subfamily A Cys Cys member 2, Small-inducible cytokine A2, SMC CF, SMC-CF, SMCCF.

Background: Chemotactic factor that attracts monocytes and basophils but not neutrophils or eosinophils. Augments monocyte anti-tumor activity. Has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis or atherosclerosis. May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis.

Gene ID: 24770

UniProt: P14844

Pathways: Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, ER-Nucleus Signaling, Unfolded Protein Response, The Global Phosphorylation Landscape of SARS-CoV-2 Infection