MLZE antibody (AA 1-100) (Cy5)

Catalog No. ABIN6984263

The Rabbit Polyclonal anti-MLZE antibody is suitable to detect MLZE in samples from Human. It has been validated for WB, IF (cc) and IF (p).

Quick Overview for MLZE antibody (AA 1-100) (Cy5) (ABIN6984263)

Target: MLZE (Melanomaderived Leucine Zipper Extra-Nuclear Factor (MLZE))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MLZE antibody is conjugated to Cy5

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-MLZE Antibody (Cy5)

Binding Specificity: AA 1-100

Cross-Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GSDMC

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for MLZE

Target: MLZE (Melanomaderived Leucine Zipper Extra-Nuclear Factor (MLZE))

Alternative Name: GSDMC

Background:

Synonyms: Gasdermin C, Gasdermin-C, GSDMC, GSDMC_HUMAN, Melanoma derived leucine zipper, extra nuclear factor, Melanoma-derived leucine zipper-containing extranuclear factor, MLZE

Background: The N-terminal moiety promotes pyroptosis. May be acting by homooligomerizing within the membrane and forming pores (PubMed:27281216). The physiological relevance of this observation is unknown (Probable).

Gene ID: 56169

UniProt: Q9BYG8