Angiotensin III antibody (AA 35-41) (Cy5)

Catalog No. ABIN6984548

The Rabbit Polyclonal anti-Angiotensin III antibody has been validated for WB, IF (cc) and IF (p). It is suitable to detect Angiotensin III in samples from Human, Mouse and Rat.

Quick Overview for Angiotensin III antibody (AA 35-41) (Cy5) (ABIN6984548)

Target: Angiotensin III (AGT3)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Angiotensin III antibody is conjugated to Cy5

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-Angiotensin III Antibody (Cy5)

Binding Specificity: AA 35-41

Specificity: The immunogen used generate this antibody is RVYIHPF, corresponding to amino acids 35-41 of human Angiotensinogen.

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide of human Angiotensin III

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for Angiotensin III

Target: Angiotensin III (AGT3)

Alternative Name: Angiotensin 3

Background:

Synonyms: Alpha 1 antiproteinase, antitrypsin, Ang II, ANG III, Angiotensin I, Angiotensin II, Angiotensin III, Angiotensinogen, Angiotensinogen serpin peptidase inhibitor, clade A member 8, ANHU, Pre angiotensinogen, Serine or cysteine proteinase inhibitor, Serpin A8, SERPINA8, AT-2, AT-II, ANGT_HUMAN.

Background: Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis. Angiotensin-2: acts directly on vascular smooth muscle as a potent vasoconstrictor, affects cardiac contractility and heart rate through its action on the sympathetic nervous system, and alters renal sodium and water absorption through its ability to stimulate the zona glomerulosa cells of the adrenal cortex to synthesize and secrete aldosterone. Angiotensin-3: stimulates aldosterone release. Angiotensin 1-7: is a ligand for the G-protein coupled receptor MAS1. Has vasodilator and antidiuretic effects. Has an antithrombotic effect that involves MAS1-mediated release of nitric oxide from platelets.

Gene ID: 183