NME2 antibody (AA 1-100) (HRP)

Catalog No. ABIN6987732

This anti-NME2 antibody is a Rabbit Polyclonal antibody detecting NME2 in ELISA, IHC (p) and IHC (fro). Suitable for Human and Mouse.

Quick Overview for NME2 antibody (AA 1-100) (HRP) (ABIN6987732)

Target: NME2 (Nucleoside diphosphate kinase B (NME2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NME2 antibody is conjugated to HRP

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-NME2 Antibody (HRP)

Binding Specificity: AA 1-100

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat,Cow,Sheep,Pig,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Nm23-H2/NME2

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for NME2

Target: NME2 (Nucleoside diphosphate kinase B (NME2))

Alternative Name: Nm23-H2/NME2

Background:

Synonyms: nucleoside dIPhosphatase kinase B, C myc purine binding transcription factor PUF, NDK B, NDKB, NDP kinase B, NDPKB, NM23 H2, NM23B, Nucleoside diphosphate kinase B, nm23-M2, NME2, Nucleoside diphosphate kinase alpha, p18-12d, puf, MGC107562, MGC107563, MGC111212, non-metastatic cells 2, protein (NM23B)expressed in, NDKB_HUMAN, C-myc purine-binding transcription factor PUF, Histidine protein kinase NDKB, nm23-H2.

Background: Major role in the synthesis of nucleoside triphosphates other than ATP. Negatively regulates Rho activity by interacting with AKAP13/LBC. Acts as a transcriptional activator of the MYC gene, binds DNA non-specifically (PubMed:8392752). Exhibits histidine protein kinase activity.

Gene ID: 4831

UniProt: P22392