GSG2 antibody (AA 421-520) (HRP)

Catalog No. ABIN6987797

The Rabbit Polyclonal anti-GSG2 antibody has been validated for WB. It is suitable to detect GSG2 in samples from Mouse and Rat.

Quick Overview for GSG2 antibody (AA 421-520) (HRP) (ABIN6987797)

Target: GSG2 (Germ Cell Associated 2 (Haspin) (GSG2))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GSG2 antibody is conjugated to HRP

Application: Western Blotting (WB)

Product Details anti-GSG2 Antibody (HRP)

Binding Specificity: AA 421-520

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from mouse Haspin

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for GSG2

Target: GSG2 (Germ Cell Associated 2 (Haspin) (GSG2))

Alternative Name: Haspin

Background:

Synonyms: germ cell associated 2, Germ cell-specific gene 2 protein, GSG2, H-Haspin, Haploid germ cell-specific nuclear protein kinase, HASP_HUMAN, Serine/threonine-protein kinase Haspin.

Background: Serine/threonine-protein kinase that phosphorylates histone H3 at 'Ser-3' (H3T3ph) during mitosis. This positions and activates AURKB and other components of the chromosomal passenger complex (CPC) at centromeres to ensure proper chromatid cohesion, metaphase alignment and normal progression through the cell cycle.

Gene ID: 83903

UniProt: Q9Z0R0