Snail + Slug (pSer246) antibody (HRP)
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- Target
- Snail + Slug
- Binding Specificity
- pSer246
- Reactivity
- Human, Rat
-
Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- HRP
-
Application
- Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Cross-Reactivity
- Human, Rat
- Predicted Reactivity
- Mouse,Cow,Sheep,Pig,Horse,Rabbit
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human phospho-SNAIL + SLUG (Ser246)
- Isotype
- IgG
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-
- Application Notes
- IHC-P 1:200-400
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
-
- Target
- Snail + Slug
- Background
-
Synonyms: SNAIL + SLUG (phospho S246), p-SNAIL + SLUG (phospho S246), SNAIL + SLUG (phospho S246 + S251), SNAIL + SLUG (phospho Ser246 + Ser251), phospho-SNAIL(Ser246) + SLUG(Ser251), phospho-SNAIL(Ser246) + SLUG(Ser251), dJ710H13.1, MGC10182, Neural crest transcription factor Slug, Protein sna, Protein snail homolog 1, Protein snail homolog 2, Protein snail homolog, Slug homolog zinc finger protein, Slug zinc finger protein, SLUGH, SLUGH 1, SLUGH1, SLUGH2, SNA, Sna protein, SNAH, SNAI 2, snai1, SNAI1_HUMAN, Snai2, SNAI2_HUMAN, Snail 2, Snail homolog 1 (Drosophila), Snail homolog 2, Snail2, WS 2D, WS2D, Zinc finger protein SLUG, Zinc finger protein SNAI1, Zinc finger protein SNAI2.
Background: Involved in the epithelial to mesenchymal transition (EMT) and formation and maintenance of embryonic mesoderm. Binds to 3 E-boxes of the E-cadherin gene promoter and represses its transcription.
- Gene ID
- 6615
- UniProt
- O95863
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