CYP26A1 antibody (AA 200-400) (HRP)

Catalog No. ABIN6988075

This Rabbit Monoclonal antibody specifically detects CYP26A1 in WB and IHC (p). It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for CYP26A1 antibody (AA 200-400) (HRP) (ABIN6988075)

Target: CYP26A1 (Cytochrome P450, Family 26, Subfamily A, Polypeptide 1 (CYP26A1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This CYP26A1 antibody is conjugated to HRP

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 11A1

Product Details anti-CYP26A1 Antibody (HRP)

Binding Specificity: AA 200-400

Purification: Purified by Protein A.

Immunogen: Recombinant human CYP26A1

Isotype: IgG

Application Details

Application Notes: WB 1:300-1000
IHC-P 1:200-400

Restrictions: For Research Use only

Handling

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % Gentamicin.

Storage: 4 °C

Storage Comment: Store at 4°C

Expiry Date: 12 months

Target Details for CYP26A1

Target: CYP26A1 (Cytochrome P450, Family 26, Subfamily A, Polypeptide 1 (CYP26A1))

Alternative Name: CYP26A1

Background:

Plays a key role in retinoic acid metabolism. Acts on retinoids, including all-trans-retinoic acid (RA) and its stereoisomer 9-cis-RA. Capable of both 4-hydroxylation and 18-hydroxylation. Responsible for generation of several hydroxylated forms of RA, including 4-OH-RA, 4-oxo-RA and 18-OH-RA. Subcellular Location : Endoplasmic reticulum membrane. Microsome membrane.

Subcellular location: Cytoplasm, Cytomembrane

Synonyms: CP26, CP26A_HUMAN, CYP26, CYP26A 1, cyp26a1, Cytochrome P450 26A1, Cytochrome P450 family 26 subfamily A polypeptide 1, Cytochrome P450 retinoic acid-inactivating 1, cytochrome P450, family 26, subfamily A, polypeptide 1, cytochrome P450, subfamily XXVIA, polypeptide 1, Cytochrome P450RAI, hP450RAI, OTTHUMP00000020102, OTTHUMP00000020103, P450, P450 retinoic acid inactivating 1, P450RAI, P450RAI1, Retinoic acid 4 hydroxylase, Retinoic acid 4-hydroxylase, Retinoic acid metabolizing cytochrome, Retinoic acid-metabolizing cytochrome.

Gene ID: 1592

UniProt: O43174

Pathways: Retinoic Acid Receptor Signaling Pathway, Monocarboxylic Acid Catabolic Process