HOXD10 antibody (AA 111-210)

Catalog No. ABIN6988988

The Rabbit Polyclonal anti-HOXD10 antibody has been validated for IHC (p) and IHC (fro). It is suitable to detect HOXD10 in samples from Rat.

Quick Overview for HOXD10 antibody (AA 111-210) (ABIN6988988)

Target: HOXD10 (Homeobox D10 (HOXD10))

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HOXD10 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-HOXD10 Antibody

Binding Specificity: AA 111-210

Cross-Reactivity: Rat

Predicted Reactivity: Human,Mouse,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human HOXD10

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for HOXD10

Target: HOXD10 (Homeobox D10 (HOXD10))

Alternative Name: HOXD10

Background:

Synonyms: Homeo box D10, Homeobox protein Hox-4D, Homeobox protein Hox-4E, Homeobox protein Hox-D10, Hox 4.5, Hox 4D, Hox 4E, HOX4D, HOXD10, HXD10, HXD10_HUMAN, Hox 5.3.

Background: This gene is a member of the Abd-B homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox D genes located on chromosome 2. The encoded nuclear protein functions as a sequence-specific transcription factor that is expressed in the developing limb buds and is involved in differentiation and limb development. Mutations in this gene have been associated with Wilm's tumor and congenital vertical talus (also known as "rocker-bottom foot" deformity or congenital convex pes valgus) and/or a foot deformity resembling that seen in Charcot-Marie-Tooth disease. [provided by RefSeq, Jul 2008]

Gene ID: 3236

UniProt: P28358