EDARADD antibody (AA 1-100)

Catalog No. ABIN6989179

This Rabbit Polyclonal antibody specifically detects EDARADD in WB, IF (cc), IF (p), ELISA, IHC (fro), IHC (p) and ICC. It exhibits reactivity toward Mouse.

Quick Overview for EDARADD antibody (AA 1-100) (ABIN6989179)

Target: EDARADD (EDAR-Associated Death Domain (EDARADD))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EDARADD antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Product Details anti-EDARADD Antibody

Binding Specificity: AA 1-100

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human EDARADD

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for EDARADD

Target: EDARADD (EDAR-Associated Death Domain (EDARADD))

Alternative Name: EDARADD

Background:

Synonyms: Cr, Crinkled homolog, ectodysplasia A receptor associated death domain, Ectodysplasin-A receptor-associated adapter protein, ED3, EDA3, EDAD_HUMAN, EDAR associated death domain, EDAR-associated death domain protein, EDARADD, Protein crinkled homolog.

Background: Adapter protein that interacts with EDAR DEATH domain and couples the receptor to EDA signaling pathway during morphogenesis of ectodermal organs. Mediates the activation of NF-kappa-B.

Gene ID: 128178

UniProt: Q8WWZ3

Pathways: Ubiquitin Proteasome Pathway