IRAK3 antibody (AA 151-250)

Catalog No. ABIN6989189

The Rabbit Polyclonal anti-IRAK3 antibody is suitable to detect IRAK3 in samples from Mouse. It has been validated for WB, ELISA, ICC, IHC (p), IF (cc), IF (p) and IHC (fro).

Quick Overview for IRAK3 antibody (AA 151-250) (ABIN6989189)

Target: IRAK3 (Interleukin-1 Receptor-Associated Kinase 3 (IRAK3))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IRAK3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-IRAK3 Antibody

Binding Specificity: AA 151-250

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human IRAKM

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for IRAK3

Target: IRAK3 (Interleukin-1 Receptor-Associated Kinase 3 (IRAK3))

Alternative Name: IRAKM

Background:

Synonyms: ASRT5, IL 1 receptor associated kinase M, IL-1 receptor-associated kinase M, IL1 receptor associated kinase M, Interleukin 1 Receptor Associated Kinase 3, Interleukin 1 Receptor Associated Kinase 3, Interleukin 1 Receptor Associated Kinase M, Interleukin 1 Receptor Associated Kinase M, Interleukin-1 receptor-associated kinase 3, IRAK 3, IRAK 3, IRAK M, IRAK-3, IRAK-M, IRAK3_HUMAN.

Background: Inhibits dissociation of IRAK1 and IRAK4 from the Toll-like receptor signaling complex by either inhibiting the phosphorylation of IRAK1 and IRAK4 or stabilizing the receptor complex.

Gene ID: 11213

UniProt: Q9Y616

Pathways: TLR Signaling, Activation of Innate immune Response, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades