TMEM175 antibody (AA 231-330)

Catalog No. ABIN6989246

The Rabbit Polyclonal anti-TMEM175 antibody has been validated for WB, ELISA, IF (cc), IF (p), IHC (fro), IHC (p) and ICC. It is suitable to detect TMEM175 in samples from Mouse and Rat.

Quick Overview for TMEM175 antibody (AA 231-330) (ABIN6989246)

Target: TMEM175 (Transmembrane Protein 175 (TMEM175))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TMEM175 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Product Details anti-TMEM175 Antibody

Binding Specificity: AA 231-330

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TM175

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for TMEM175

Target: TMEM175 (Transmembrane Protein 175 (TMEM175))

Alternative Name: TMEM175

Background:

Synonyms: MGC4618, Hypothetical protein DKFZp547K246, hypothetical protein LOC84286, Hypothetical protein MGC4618, TM175_HUMAN, tmem175, Transmembrane protein 175.

Background: Organelle-specific potassium channel specifically responsible for potassium conductance in endosomes and lysosomes. Forms a potassium-permeable leak-like channel, which regulates lumenal pH stability and is required for autophagosome-lysosome fusion. Constitutes the major lysosomal potassium channel.

Gene ID: 84286

UniProt: Q9BSA9