RSPO1 antibody (AA 31-130)

Catalog No. ABIN6989307

This anti-RSPO1 antibody is a Rabbit Polyclonal antibody detecting RSPO1 in IF (cc) and IHC (p). Suitable for Human, Rat, Mouse, Cow, Dog, Horse, Pig and Rabbit.

Quick Overview for RSPO1 antibody (AA 31-130) (ABIN6989307)

Target: RSPO1 (R-Spondin 1 (RSPO1))

Reactivity: Human, Rat, Mouse, Cow, Dog, Horse, Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RSPO1 antibody is un-conjugated

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-RSPO1 Antibody

Binding Specificity: AA 31-130

Cross-Reactivity: Cow, Dog, Horse, Human, Mouse, Pig, Rabbit, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human RSPO1

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for RSPO1

Target: RSPO1 (R-Spondin 1 (RSPO1))

Alternative Name: RSPO1

Background:

Synonyms: CRISTIN3, FLJ40906, hRspo1, R spondin homolog (Xenopus laevis), R spondin homolog, R spondin1, R-spondin-1, Roof plate specific spondin, Roof plate-specific spondin-1, RP11-566C13.1, RSPO, Rspo1, RSPO1_HUMAN.

Background: RSPO1 is a member of the R-spondin family and encodes a secreted activator protein with two cystein-rich, furin-like domains and one thrombospondin type 1 domain. In mice, the protein induces the rapid onset of crypt cell proliferation and increases intestinal epithelial healing, providing a protective effect against chemotherapy-induced adverse effects.

Gene ID: 284654

UniProt: Q2MKA7