NME2 antibody (AA 1-100)

Catalog No. ABIN6989317

This Rabbit Polyclonal antibody specifically detects NME2 in ELISA, ICC, IHC (p), IF (cc), IF (p) and IHC (fro). It exhibits reactivity toward Human and Mouse.

Quick Overview for NME2 antibody (AA 1-100) (ABIN6989317)

Target: NME2 (Nucleoside diphosphate kinase B (NME2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NME2 antibody is un-conjugated

Application: ELISA, Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-NME2 Antibody

Binding Specificity: AA 1-100

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat,Cow,Sheep,Pig,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Nm23-H2/NME2

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for NME2

Target: NME2 (Nucleoside diphosphate kinase B (NME2))

Alternative Name: Nm23-H2/NME2

Background:

Synonyms: nucleoside dIPhosphatase kinase B, C myc purine binding transcription factor PUF, NDK B, NDKB, NDP kinase B, NDPKB, NM23 H2, NM23B, Nucleoside diphosphate kinase B, nm23-M2, NME2, Nucleoside diphosphate kinase alpha, p18-12d, puf, MGC107562, MGC107563, MGC111212, non-metastatic cells 2, protein (NM23B)expressed in, NDKB_HUMAN, C-myc purine-binding transcription factor PUF, Histidine protein kinase NDKB, nm23-H2.

Background: Major role in the synthesis of nucleoside triphosphates other than ATP. Negatively regulates Rho activity by interacting with AKAP13/LBC. Acts as a transcriptional activator of the MYC gene, binds DNA non-specifically (PubMed:8392752). Exhibits histidine protein kinase activity.

Gene ID: 4831

UniProt: P22392