BCAM antibody

Catalog No. ABIN6989637

This anti-BCAM antibody is a Rabbit Monoclonal antibody detecting BCAM in WB, FACS and IHC (p). Suitable for Human.

Quick Overview for BCAM antibody (ABIN6989637)

Target: BCAM (Basal Cell Adhesion Molecule (Lutheran Blood Group) (BCAM))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This BCAM antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 8F16

Product Details anti-BCAM Antibody

Cross-Reactivity: Human

Purification: Purified by Protein A.

Immunogen: Recombinant protein corresponding to C-terminal human CD239

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
FCM 1:20-100
IHC-P 1:200-400

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for BCAM

Target: BCAM (Basal Cell Adhesion Molecule (Lutheran Blood Group) (BCAM))

Alternative Name: CD239

Background:

Synonyms: Antigen identified by monoclonal antibody F8 antibody, AU antibody, Auberger B antigen antibody, B CAM cell surface glycoprotein antibody, B cell adhesion molecule antibody, B-CAM cell surface glycoprotein antibody, Basal cell adhesion molecule (Lu and Au blood groups) antibody, Basal cell adhesion molecule (Lutheran blood group) antibody, Basal cell adhesion molecule antibody, Basal cell adhesion molecule Lu and Au blood groups antibody, Basal cell adhesion molecule Lutheran blood group antibody, Bcam antibody, BCAM_HUMAN antibody, CD239 antibody, CD239 antigen antibody, F8/G253 antigen antibody, Glycoprotein 95 kDa antibody, LU antibody, Lutheran antibody, Lutheran antigen antibody, Lutheran blood group (Auberger b antigen included) antibody, Lutheran blood group Auberger b antigen included antibody, Lutheran blood group glycoprotein antibody, MSK19 antibody

Background: This gene encodes Lutheran blood group glycoprotein, a member of the immunoglobulin superfamily and a receptor for the extracellular matrix protein, laminin. The protein contains five extracellular immunoglobulin domains, a single transmembrane domain, and a short C-terminal cytoplasmic tail. This protein may play a role in epithelial cell cancer and in vaso-occlusion of red blood cells in sickle cell disease. Polymorphisms in this gene define some of the antigens in the Lutheran system and also the Auberger system. Inactivating variants of this gene result in the recessive Lutheran null phenotype, Lu(a-b-), of the Lutheran blood group. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012].

Gene ID: 4059

UniProt: P50895