BCAM antibody (AA 32-197)

Catalog No. ABIN7193337

The Mouse Monoclonal anti-BCAM antibody (Clone 5C5A6) (ABIN7193337) specifically detects BCAM in IHC, ELISA and FACS. The antibody is reactive with Human samples.

Quick Overview for BCAM antibody (AA 32-197) (ABIN7193337)

Target: BCAM (Basal Cell Adhesion Molecule (Lutheran Blood Group) (BCAM))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This BCAM antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)

Clone: 5C5A6

Product Details anti-BCAM Antibody

Binding Specificity: AA 32-197

Purpose: CD239 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human CD239 (AA: 32-197) expressed in E. Coli.

Isotype: IgG2a

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for BCAM

Target: BCAM (Basal Cell Adhesion Molecule (Lutheran Blood Group) (BCAM))

Alternative Name: CD239

Background:

This gene encodes Lutheran blood group glycoprotein, a member of the immunoglobulin superfamily and a receptor for the extracellular matrix protein, laminin. The protein contains five extracellular immunoglobulin domains, a single transmembrane domain, and a short C-terminal cytoplasmic tail. This protein may play a role in epithelial cell cancer and in vaso-occlusion of red blood cells in sickle cell disease. Polymorphisms in this gene define some of the antigens in the Lutheran system and also the Auberger system. Inactivating variants of this gene result in the recessive Lutheran null phenotype, Lu(a-b-), of the Lutheran blood group. Two transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 67.4 kDa