MUM1 antibody

Catalog No. ABIN6989671

This Rabbit Monoclonal antibody specifically detects MUM1 in WB, IHC and IHC (p). It exhibits reactivity toward Human.

Quick Overview for MUM1 antibody (ABIN6989671)

Target: MUM1 (Melanoma Associated Antigen (Mutated) 1 (MUM1))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This MUM1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 6H0

Product Details anti-MUM1 Antibody

Cross-Reactivity: Human

Purification: Purified by Protein A.

Immunogen: Synthetic Peptide within N terminal human MUM1.

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC()

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for MUM1

Target: MUM1 (Melanoma Associated Antigen (Mutated) 1 (MUM1))

Alternative Name: MUM1

Background:

Synonyms: "Interferon regulatory factor 4 antibody, IRF 4 antibody, IRF-4 antibody, Irf4 antibody, IRF4_HUMAN antibody, LSIRF antibody, Lymphocyte specific interferon regulatory factor antibody, Lymphocyte specific IRF antibody, Lymphocyte-specific interferon regulatory factor antibody, Multiple myeloma oncogene 1 antibody, MUM 1 antibody, MUM1 antibody, NF EM5 antibody, NF-EM5 antibody, NFEM5 antibody, PU.1 interaction partner antibody, Sfpi1/PU.1 interaction partner antibody, Transcriptional activator PIP antibody"

Background: The protein encoded by this gene belongs to the IRF (interferon regulatory factor) family of transcription factors, characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. This family member is lymphocyte specific and negatively regulates Toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t(6,14)(p25,q32), may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2010]

Gene ID: 3662

UniProt: Q15306

Pathways: Chromatin Binding