MUM1 antibody (AA 671-699)
Quick Overview for MUM1 antibody (AA 671-699) (ABIN3028831)
Target
See all MUM1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 671-699
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Purpose
- MUM1 Antibody / Mutated melanoma-associated antigen 1
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Purification
- Antigen affinity
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Immunogen
- A portion of amino acids 671-699 from the human protein was used as the immunogen for this MUM1 antibody.
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Isotype
- Ig Fraction
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Application Notes
- Titration of the MUM1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Aliquot the MUM1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- MUM1 (Melanoma Associated Antigen (Mutated) 1 (MUM1))
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Alternative Name
- MUM1
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Background
- Involved in the DNA damage response pathway by contributing to the maintenance of chromatin architecture. Recruited to the vicinity of DNA breaks by TP53BP1 and plays an accessory role to facilitate damage-induced chromatin changes and promoting chromatin relaxation. Required for efficient DNA repair and cell survival following DNA damage.
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UniProt
- Q2TAK8
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Pathways
- Chromatin Binding
Target
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