LPP antibody

Catalog No. ABIN6989708

The Rabbit Monoclonal anti-LPP antibody is suitable to detect LPP in samples from Human, Mouse and Rat. It has been validated for WB and IHC (p).

Quick Overview for LPP antibody (ABIN6989708)

Target: LPP (Lipoma-preferred partner (LPP))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This LPP antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 2H15

Product Details anti-LPP Antibody

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: Synthetic peptide within N-terminal Human LPP.

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for LPP

Target: LPP (Lipoma-preferred partner (LPP))

Alternative Name: LPP

Background:

Synonyms: DKFZp779O0231 antibody, FLJ30652 antibody, FLJ41512 antibody, LIM domain containing preferred translocation partner in lipoma antibody, LIM domain-containing preferred translocation partner in lipoma antibody, LIM protein antibody, Lipoma preferred partner antibody, Lipoma-preferred partner antibody, lpp antibody, LPP_HUMAN antibody

Background: LPP (LIM containing lipoma preferred partner), is a scaffolding protein which contains three LIM domains at its carboxy terminus, preceded by a proline rich pre LIM region containing a number of protein interaction domains. LPP localizes to sites of cell adhesion, such as focal adhesions and cell-cell contacts and may be involved in cell-cell adhesion and cell motility. LPP also shuttles through the nucleus and may function as a transcriptional co-activator. The human LPP gene maps to chromosomal location 3q28, and preferentially translocates to the HMGIC gene in a subclass of human benign mesenchymal tumors known as lipomas. Alternate splicing results in multiple transcript variants.

Gene ID: 4026

UniProt: Q93052