CTNNA3 antibody

Catalog No. ABIN6989713

This Rabbit Monoclonal antibody specifically detects CTNNA3 in WB and IHC (p). It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for CTNNA3 antibody (ABIN6989713)

Target: CTNNA3 (Catenin (Cadherin-Associated Protein), alpha 3 (CTNNA3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This CTNNA3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 3H55

Product Details anti-CTNNA3 Antibody

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: Recombinant fragment within C-terminal Human CTNNA3.

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for CTNNA3

Target: CTNNA3 (Catenin (Cadherin-Associated Protein), alpha 3 (CTNNA3))

Alternative Name: CTNNA3

Background:

Synonyms: 4930429L08Rik antibody, 4933408A16 antibody, Alpha catenin like protein antibody, Alpha T catenin antibody, Alpha T-catenin antibody, Cadherin associated protein antibody, Cadherin-associated protein antibody, Catenin alpha 3 antibody, Catenin alpha-3 antibody, Catna3 antibody, CTNA3_HUMAN antibody, CTNNA3 antibody, MGC26194 antibody, MGC75041 antibody, OTTHUMP00000019684 antibody, OTTMUSP00000028119 antibody, OTTMUSP00000028120 antibody, RP11-433J16.1 antibody, VR22 antibody

Background: The catenins are ubiquitously expressed, cytoplasmic proteins that associate with E-cadherin at cellular junctions. Catenin/cadherin complexes play an important role in mediating cellular adhesion. alpha T-catenin, also referred to as VR22, is a 895-amino acid protein that is most abundantally expressed in cardiomyocytes and in the peritubular myoid cells of the testis. alpha T-catenin binds to alpha E-catenin as well as to beta-catenin, and it functions to inhibit Wnt signaling. CTNNA3, the gene that encodes for alpha-T-catenin, is located on chromosome 10, and mutations in this gene show a strong correlation to late-onset Alzheimer's disease (LOAD) as well as to dilated cardiomyopathy.

Gene ID: 29119

UniProt: Q9UI47