YAP1 antibody (pSer127)

Catalog No. ABIN6989717

The Rabbit Monoclonal anti-YAP1 antibody has been validated for IHC (p) and FACS. It is suitable to detect YAP1 in samples from Human, Mouse and Rat.

Quick Overview for YAP1 antibody (pSer127) (ABIN6989717)

Target: YAP1 (Yes-Associated Protein 1 (YAP1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This YAP1 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Clone: 1H12

Product Details anti-YAP1 Antibody

Binding Specificity: pSer127

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: Synthetic peptide derived from human YAP1 (S127), around 100-150aa (phospho S127).

Isotype: IgG

Application Details

Application Notes: FCM 1:20-100
IHC-P 1:200-400

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for YAP1

Target: YAP1 (Yes-Associated Protein 1 (YAP1))

Alternative Name: YAP1

Background:

Synonyms: 65 kDa Yes associated protein, YAp 1, YAp-1, YAP 65, YAP, YAP2, YAP65, Yes associated protein 1 65 kDa, Yes associated protein 1, Yes associated protein 2, YKI.

Background: YAP1 (also known as Yes associated protein 1) was originally identified as a transcription factor that binds to the SH3 domain of the YES kinase (a Src protein kinase). More recently it has been identified as a candidate oncogene that promotes tumorigenesis in many different types of cancer.

Gene ID: 10413

UniProt: P46937

Pathways: MAPK Signaling, Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha