Calpastatin antibody

Catalog No. ABIN6989752

This Rabbit Polyclonal antibody specifically detects Calpastatin in WB. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for Calpastatin antibody (ABIN6989752)

Target: Calpastatin (CAST)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Calpastatin antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Calpastatin Antibody

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 550-650 of human CAST (NP_001177371.1).

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for Calpastatin

Target: Calpastatin (CAST)

Alternative Name: CAST

Background:

Synonyms: CAST,BS-17,PLACK

Background: The protein encoded by this gene is an endogenous calpain (calcium-dependent cysteine protease) inhibitor. It consists of an N-terminal domain L and four repetitive calpain-inhibition domains (domains 1-4), and it is involved in the proteolysis of amyloid precursor protein. The calpain/calpastatin system is involved in numerous membrane fusion events, such as neural vesicle exocytosis and platelet and red-cell aggregation. The encoded protein is also thought to affect the expression levels of genes encoding structural or regulatory proteins. Alternatively spliced transcript variants encoding different isoforms have been described.

Gene ID: 831

UniProt: P20810