Calpastatin antibody (AA 431-530)

Catalog No. ABIN720161

There is 1 publication for this product available. The Rabbit Polyclonal anti-Calpastatin antibody is suitable to detect Calpastatin in samples from Human. It has been validated for WB, IHC (p), IF (cc), IF (p) and IHC (fro).

Quick Overview for Calpastatin antibody (AA 431-530) (ABIN720161)

Target: Calpastatin (CAST)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Calpastatin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-Calpastatin Antibody

Binding Specificity: AA 431-530

Purpose: Calpastatin Polyclonal Antibody

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat,Cow

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Calpastatin

Isotype: IgG

Application Details

Application Notes: WB(1:300-5000),

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-Calpastatin antibody (ABIN720161)

Huang, Rose, Hoffmann, Hashimoto, Bertino, Denk, Takano, Iwata, Saido, Hoffmann: "Calpastatin prevents NF-?B-mediated hyperactivation of macrophages and attenuates colitis." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 191, Issue 7, pp. 3778-88, (2013) (PubMed).

Target Details for Calpastatin

Target: Calpastatin (CAST)

Alternative Name: Calpastatin

Background:

Synonyms: BS-17, Calpastatin, Calpain inhibitor, Sperm BS-17 component, CAST

Background: Specific inhibition of calpain (calcium-dependent cysteine protease). Plays a key role in postmortem tenderization of meat and have been proposed to be involved in muscle protein degradation in living tissue.

Gene ID: 831

UniProt: P20810