The Rabbit Monoclonal anti-SARS-CoV-2 Nucleocapsid antibody has been validated for ELISA, WB, IF, FACS, IHC and IP. It is suitable to detect SARS-CoV-2 Nucleocapsid in samples from SARS Coronavirus-2 (SARS-CoV-2).
Catalog No. ABIN6989972
Quick Overview for SARS-CoV-2 Nucleocapsid antibody (ABIN6989972)
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C,4 °C
Storage Comment
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Target
SARS-CoV-2 Nucleocapsid (SARS-CoV-2 N)
Alternative Name
SARS-CoV-2 Nucleocapsid
Target Type
Viral Protein
Background
Coronaviruses are enveloped viruses with a positive-sense RNA genome and with a nucleocapsid of helical symmetry. Coronavirus nucleoproteins localize to the cytoplasm and the nucleolus, a subnuclear structure, in both virus-infected primary cells and in cells transfected with plasmids that express N protein. Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. During virion assembly, N protein binds to viral RNA and leads to formation of the helical nucleocapsid. Nucleocapsid protein is a highly immunogenic phosphoprotein also implicated in viral genome replication and in modulating cell signaling pathways. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool.