SARS-CoV-2 N
Reactivity: SARS Coronavirus-2 (SARS-CoV-2), SARS Coronavirus (SARS-CoV)
ELISA, IF, Neut
Host: Human
Monoclonal
CR3018 (03-018)
unconjugated
Recombinant Antibody
Application Notes
Immunoreactivity: 80-120 % compared to the reference sample in an ELISA test.
Restrictions
For Research Use only
Format
Liquid
Concentration
5.0 mg/mL
Buffer
PBS, pH 7.4
Storage
-20 °C,4 °C
Storage Comment
24 months from manufacturing at <-20 °C, 1 month, 2 to 8 °C under sterile conditions.
Target
SARS-CoV-2 Nucleocapsid (SARS-CoV-2 N)
Alternative Name
SARS-CoV-2 Nucleocapsid
Target Type
Viral Protein
Background
Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. N protein packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M. Plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool.