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SARS-CoV-2 Membrane Protein antibody (AA 130-180)

SARS-CoV-2 M Reactivity: SARS Coronavirus-2 (SARS-CoV-2) ELISA, WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6990136
  • Target See all SARS-CoV-2 Membrane Protein (SARS-CoV-2 M) products
    SARS-CoV-2 Membrane Protein (SARS-CoV-2 M)
    Binding Specificity
    • 3
    • 1
    AA 130-180
    Reactivity
    • 5
    • 1
    SARS Coronavirus-2 (SARS-CoV-2)
    Host
    • 3
    • 2
    Rabbit
    Clonality
    • 5
    Polyclonal
    Conjugate
    • 5
    This SARS-CoV-2 Membrane Protein antibody is un-conjugated
    Application
    ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
    Purification
    SARS-CoV-2 (COVID-19) Membrane Antibody is affinity chromatography
    Immunogen
    Anti-SARS-CoV-2 (COVID-19) Membrane antibody was raised against a peptide corresponding to 13 amino acids near the center of SARS-CoV-2 (COVID-19) Membrane protein. The immunogen is located between 130-180 amino acids of the SARS-CoV-2 (COVID-19) Membrane protein.
    Isotype
    IgG
  • Application Notes
    WB: 0.25 μ,g/mL, IHC: 0.5 μ,g/mL

    Antibody validated: Immunohistochemistry in human samples. SARS-CoV-2 (COVID-19) Membrane antibody can detect 2 ng of free peptide at 1 μ,g/mL in ELISA. It can detect SARS-CoV-2 Membrane recombinant protein by ELISA and WB. All other applications and species not yet tested.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    SARS-CoV-2 (COVID-19) Membrane Antibody is supplied in PBS containing 0.02 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,4 °C
    Storage Comment
    SARS-CoV-2 (COVID-19) Membrane antibody can be stored at 4 ° C for three months and -20 ° C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Target
    SARS-CoV-2 Membrane Protein (SARS-CoV-2 M)
    Alternative Name
    SARS-CoV-2 Membrane Protein (SARS-CoV-2 M Products)
    Synonyms
    membrane glycoprotein antibody, M antibody
    Target Type
    Viral Protein
    Background
    Coronavirus disease 2019 (COVID-19), formerly known as 2019-nCoV acute respiratory disease, is an infectious disease caused by SARS-CoV-2, a virus closely related to the SARS virus. The disease is the cause of the 2019-20 coronavirus outbreak (1). SARS-CoV-2 is the seventh member of the enveloped, positive-stranded RNA viruses that are able to infect humans. The SARS-CoV-2 genome, like other coronaviruses, encodes for multiple structural and nonstructural proteins. The structural proteins include spike protein (S), envelope protein (E), membrane glycoprotein (M), nucleocapsid phosphoprotein (N), and the nonstructural proteins include open reading frame 1ab (ORF1ab), ORF3a, ORF6, ORF7a, ORF8, and ORF10 (2).The membrane (M) protein or matrix protein is the most abundant structural protein and defines the shape of the viral envelope (3). It is an integral membrane protein involved in the budding of the viral particles and interacts with S (Spike) protein. It involves in organization of the nucleoprotein inside, which includes many copies of the N (nucleocapsid) protein bound to the genomic RNA. The M protein holds dominant cellular immunogenicity and has been determined as a protective antigen in humoral responses, which suggests it would serve as a potential target in vaccine design (4).
    Gene ID
    43740571
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