CCR8 antibody (AA 170-220)

Catalog No. ABIN6990287

The Rabbit Polyclonal anti-CCR8 antibody has been validated for WB and ELISA. It is suitable to detect CCR8 in samples from Human.

Quick Overview for CCR8 antibody (AA 170-220) (ABIN6990287)

Target: CCR8 (Chemokine (C-C Motif) Receptor 8 (CCR8))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCR8 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-CCR8 Antibody

Binding Specificity: AA 170-220

Purification: CCR8 Antibody is affinity chromatography purified via peptide column.

Immunogen: CCR8 antibody was raised against a 19 amino acid peptide near the center of human CCR8. The immunogen is located within amino acids 170 - 220 of CCR8.

Isotype: IgG

Application Details

Application Notes: CCR8 antibody can be used for detection of CCR8 by Western blot 0.5 μ,g/mL. An approximately 50 kDa band can be detected.

Antibody validated: Western Blot in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: CCR8 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: CCR8 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for CCR8

Target: CCR8 (Chemokine (C-C Motif) Receptor 8 (CCR8))

Alternative Name: CCR8

Background: CCR8 Antibody: CCR8 is one of the chemokine receptors that are required as coreceptors for HIV infection. The genes encoding human and murine CCR8 were cloned and designated TER1, CKR-L1, and ChemR1. The encoded seven transmembrane protein was identified as the receptor for human CC chemokine I-309 and renamed CCR8. Recently, CCR8 was found to serve as a coreceptor for diverse T-cell tropic, dual-tropic and macrophage-tropic HIV-1 strains. CCR8 mediates CC chemokine I-309 induced monocyte chemoattraction and HIV-1 envelope fusion and virus infection, which can be prevented by the CCR8 ligand I-309. CCR8 is expressed in spleen, thymus and T lymphoblastic cell lines.

Molecular Weight: 50 kDa

Gene ID: 1237