PLIN3 antibody (N-Term)

Catalog No. ABIN6990373

This Rabbit Polyclonal antibody specifically detects PLIN3 in WB, ELISA and IHC (p). It exhibits reactivity toward Human and Mouse.

Quick Overview for PLIN3 antibody (N-Term) (ABIN6990373)

Target: PLIN3 (Perilipin 3 (PLIN3))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PLIN3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-PLIN3 Antibody

Binding Specificity: AA 30-80, N-Term

Purification: TIP47 Antibody is affinity chromatography purified via peptide column.

Immunogen: Anti-TIP47 antibody was raised against a peptide corresponding to 14 amino acids near the amino terminus of human TIP47. The immunogen is located within amino acids 30 - 80 of TIP47.

Isotype: IgG

Application Details

Application Notes: WB: 1-4 μ,g/mL, IHC-P: 2 μ,g/mL.

Antibody validated: Western Blot in human and mouse samples, Immunohistochemistry in rat samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: TIP47 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: TIP47 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for PLIN3

Target: PLIN3 (Perilipin 3 (PLIN3))

Alternative Name: TIP47

Background: TIP47 Antibody: Tail-interacting protein (TIP47) is a cytosolic protein essential for the transport of mannose-6-phosphate receptors (MPRs) from endosomes to the trans-Golgi compartments in cells. TIP47 is recruited from the cytoplasm to the late endosomal surface by the Ras-associated protein Rab9 GTPase, enabling it to bind more efficiently to MPR cytoplasmic domains. Recently, it was shown that TIP47 regulates the expression of Rab9, as expression of siRNA to TIP47 in transfected cells dramatically decreased the half-life of the Rab9 protein in addition to stabilizing the subcellular localization of Rab9. At least two isoforms of TIP47 are known to exist.

Molecular Weight: Predicted: 47kD and 46kD

Observed: 47kD and 46kD kDa

Gene ID: 10226

UniProt: O60664