TRAF3IP2 antibody (C-Term)

Catalog No. ABIN6990384

This anti-TRAF3IP2 antibody is a Rabbit Polyclonal antibody detecting TRAF3IP2 in WB, ELISA, IF and IHC (p). Suitable for Human.

Quick Overview for TRAF3IP2 antibody (C-Term) (ABIN6990384)

Target: TRAF3IP2 (TRAF3 Interacting Protein 2 (TRAF3IP2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRAF3IP2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-TRAF3IP2 Antibody

Binding Specificity: C-Term

Purification: CIKS Antibody is affinity chromatography purified via peptide column.

Immunogen: CIKS antibody was raised against a 15 amino acid peptide near the carboxy terminus of human CIKS. The immunogen is located within the last 50 amino acids of CIKS.

Isotype: IgG

Application Details

Application Notes: CIKS antibody can be used for detection of CIKS by Western blot at 1 μ,g/mL. A band at approximately 63 kDa can be detected. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: CIKS Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: CIKS antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for TRAF3IP2

Target: TRAF3IP2 (TRAF3 Interacting Protein 2 (TRAF3IP2))

Alternative Name: CIKS

Background: CIKS Antibody: Nuclear factor kappa B (NF-κ,B) is a ubiquitous transcription factor and an essential mediator of gene expression during activation of immune and inflammatory responses. NF-κ,B mediates the expression of a great variety of genes in response to extracellular stimuli. NF-κ,B associates with Iκ,B proteins in the cell cytoplasm, which inhibit NF-κ,B activity. Iκ,B is phosphorylated by Iκ,B kinase (IKK) complex that contains IKKα, IKKβ, and IKKγ,. A novel molecule that associates with and activates IKK was recently identified and designated CIKS (for connection to IKK and SAPK/JNK) and Act1 (for NF-κ,B activator 1). CIKS directly interacts with IKKγ,. CIKS/Act1 also activates activating transcription factor (ATF) and activator protein 1 (AP-1) through Jun kinase (JNK). These results indicate that CIKS/Act1 is involved in the inflammation and stress responses. CIKS/Act1 is ubiquitously expressed in human tissues.

Molecular Weight: 63 kDa

Gene ID: 10758

UniProt: O43734

Pathways: Production of Molecular Mediator of Immune Response