CBLN1 antibody (AA 50-100)

Catalog No. ABIN6990562

This Rabbit Polyclonal antibody specifically detects CBLN1 in WB, ELISA and IHC (p). It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for CBLN1 antibody (AA 50-100) (ABIN6990562)

Target: CBLN1 (Cerebellin 1 Precursor (CBLN1))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CBLN1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-CBLN1 Antibody

Binding Specificity: AA 50-100

Purification: Precerebellin Antibody is affinity chromatography purified via peptide column.

Immunogen: Precerebellin antibody was raised against a 15 amino acid synthetic peptide from the middle of human precerebellin. The immunogen is located within amino acids 50 - 100 of Precerebellin.

Isotype: IgG

Application Details

Application Notes: Precerebellin antibody can be used for the detection of precerebellin by Western blot at 2 - 4 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2 μ,g/mL.

Antibody validated: Western Blot in mouse samples and Immunohistochemistry in rat samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Precerebellin Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: Precerebellin antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for CBLN1

Target: CBLN1 (Cerebellin 1 Precursor (CBLN1))

Alternative Name: Precerebellin

Background: Precerebellin Antibody: Precerebellin is the precursor of the brain-specific hexadecapeptide cerebellin, a protein with substantial similarity to the globular region of the B chain of complement component C1q. Cerebellin exerts neuromodulatory functions by directly stimulating norepinephrine release via the adenylate cyclase/pka- dependent signaling pathway, and indirectly enhances adrenocortical secretion in vivo, through a paracrine mechanism involving medullary catecholamine release. The active form of precerebellin is highly enriched in postsynaptic structures of cerebellar Purkinje cells in cartwheel neurons of the dorsal cochlear nucleus. Because precerebellin belongs to the C1q/tumor necrosis factor superfamily of secreted proteins and has similarity to adiponectin and CTRP3, it has been suggested that precerebellin posseses functions other than those already stated.

Gene ID: 869

UniProt: P23435