IL-9 antibody (C-Term)

Catalog No. ABIN6990654

This anti-IL-9 antibody is a Rabbit Polyclonal antibody detecting IL-9 in WB, ELISA, IF and IHC (p). Suitable for Human.

Quick Overview for IL-9 antibody (C-Term) (ABIN6990654)

Target: IL-9 (IL9) (Interleukin 9 (IL9))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL-9 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-IL-9 Antibody

Binding Specificity: C-Term

Specificity: IL-9 antibody is human specific. IL-9 antibody is predicted to no cross-react with IL-7.

Purification: IL-9 Antibody is affinity chromatography purified via peptide column.

Immunogen: Anti-IL-9 antibody was raised against a peptide corresponding to 16 amino acids near the carboxy terminus of human IL-9. The immunogen is located within the last 50 amino acids of IL-9.

Isotype: IgG

Application Details

Application Notes: WB: 1-4 μ,g/mL, IHC: 5 μ,g/mL, IF: 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples, Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: IL-9 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: IL-9 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Target Details for IL-9

Target: IL-9 (IL9) (Interleukin 9 (IL9))

Alternative Name: IL-9

Background: Interleukin 9 (IL-9) is a cytokine secreted by TH2 lymphocytes that acts as a regulator of a variety of hematopoietic cells, stimulates cell proliferation and prevents apoptosis (1,2). It functions through the interleukin 9 receptor (IL9R), which activates different signal transducer and activator (STAT) proteins (3). The IL-9 gene has been identified as a candidate gene for asthma (4). Genetic studies on a mouse model of asthma demonstrated that this cytokine is a determining factor in the pathogenesis of bronchial hyperresponsiveness (5).

Molecular Weight: Predicted: 16kD

Observed: 22 kD (Post-modification: 4 N-linked glycosylations) kDa

Gene ID: 3578

NCBI Accession: NP_000581

UniProt: P15248

Pathways: JAK-STAT Signaling